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Thioredoxin-dependent peroxide reductase, mitochondrial

Summary

UniProt ID

P30048

Gene Symbol

PRDX3
AOP1

Organism

Homo sapiens (human)

External Links

GlyGen: P30048
PubChem: P30048
The Human Metabolome Database: HMDBP03063
The O-GlcNAc Database: P30048
RaftProt: P30048

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Antioxidant
Corneal dystrophy
Cytoplasm
Direct protein sequencing
Disease variant
Disulfide bond
Endosome
Mitochondrion
Neurodegeneration
Palmitate
Peroxidase
Phosphoprotein
Redox-active center
Reference proteome
Transit peptide

Gene Ontology (GO)

Displaying entries **1 - 10** of 16 in total

1

2

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GO Term
maternal placenta development
response to oxidative stress
positive regulation of cell population proliferation
myeloid cell differentiation
negative regulation of kinase activity
cellular response to oxidative stress
cellular response to reactive oxygen species
negative regulation of apoptotic process
peptidyl-cysteine oxidation
cell redox homeostasis

Displaying **all 9** entries
GO Term
cytoplasm
plasma membrane
protein-containing complex
intracellular membrane-bounded organelle
mitochondrion
mitochondrial matrix
cytosol
nucleoplasm
early endosome

Displaying **all 5** entries
GO Term
protein kinase binding
identical protein binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
thioredoxin peroxidase activity
alkyl hydroperoxide reductase activity

Annotation information from UniProt.

Sequence

MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites