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MIRAGE
DNA replication licensing factor MCM4
Summary
- UniProt ID
- P30665
- Gene Symbol
-
- CDC54
- HCD21
- MCM4
- YP9531.13
- YPR019W
- Gene ID
- 856130
- Organism
- Saccharomyces cerevisiae S288C
Annotation
- Keyword
-
- 3D-structure
- Cell cycle
- DNA replication
- DNA-binding
- Helicase
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| DNA helicase activity |
| helicase activity |
| ATP binding |
| ATP hydrolysis activity |
| single-stranded DNA binding |
| DNA replication origin binding |
Sequence
MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEGNIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSSSSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of ATR in response to replication stress | Saccharomyces cerevisiae |
| Activation of the pre-replicative complex | Saccharomyces cerevisiae |
| Assembly of the pre-replicative complex | Saccharomyces cerevisiae |
| Switching of origins to a post-replicative state | Saccharomyces cerevisiae |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1380 | endometrial cancer |
