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S-adenosylmethionine synthase isoform type-2
Summary
- UniProt ID
- P31153
- Gene Symbol
-
- AMS2
- MAT2A
- MATA2
- Gene ID
- 4144
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Isopeptide bond
- Magnesium
- Metal-binding
- One-carbon metabolism
- Phosphoprotein
- Potassium
- Reference proteome
- Transferase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| methionine adenosyltransferase complex |
| GO Term |
|---|
| small molecule binding |
| identical protein binding |
| methionine adenosyltransferase activity |
| metal ion binding |
| ATP binding |
Sequence
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 182 |
|
|||
| 283 |
|
|||
| 288 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Methylation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1324 | lung cancer |
