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MIRAGE
T-lymphocyte activation antigen CD80
Summary
- UniProt ID
- P33681
- Gene Symbol
-
- CD28LG
- CD28LG1
- CD80
- LAB7
- Gene ID
- 941
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Host cell receptor for virus entry
- Host-virus interaction
- Immunoglobulin domain
- Palmitate
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| protein complex involved in cell adhesion |
| plasma membrane |
| external side of plasma membrane |
| cell surface |
| GO Term |
|---|
| virus receptor activity |
| coreceptor activity |
| receptor ligand activity |
Sequence
MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRRNERLRRESVRPV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 53 | N-linked (GlcNAc...) asparagine |
|
||
| 89 | N-linked (GlcNAc...) asparagine |
|
||
| 98 | N-linked (GlcNAc...) asparagine |
|
||
| 144 |
|
|
||
| 186 | N-linked (GlcNAc...) asparagine |
|
||
| 207 | N-linked (GlcNAc...) asparagine | |||
| 211 | N-linked (GlcNAc...) asparagine |
|
||
| 226 | N-linked (GlcNAc...) asparagine |
|
||
| 232 | N-linked (GlcNAc...) asparagine |
|
G80920RR
G02886BB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CD28 co-stimulation | Homo sapiens |
| CD28 dependent PI3K/Akt signaling | Homo sapiens |
| CD28 dependent Vav1 pathway | Homo sapiens |
| CTLA4 inhibitory signaling | Homo sapiens |
| Constitutive Signaling by Aberrant PI3K in Cancer | Homo sapiens |
| Interleukin-10 signaling | Homo sapiens |
| PI3K/AKT Signaling | Homo sapiens |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9744 | type 1 diabetes mellitus |
