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Polycomb complex protein BMI-1

Summary

UniProt ID

P35226

Gene Symbol

BMI1
PCGF4
RNF51

Organism

Homo sapiens (human)

External Links

GlyGen: P35226
PubChem: P35226
The O-GlcNAc Database: P35226
O-GlcNAcAtlas: P35226

Annotation

Keyword

3D-structure
Chromatin regulator
Cytoplasm
Nucleus
Proto-oncogene
Reference proteome
Repressor
Transcription regulation
Ubl conjugation
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 19 in total

1

2

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GO Term
negative regulation of apoptotic signaling pathway
embryonic skeletal system morphogenesis
positive regulation of ubiquitin-protein transferase activity
regulation of adaxial/abaxial pattern formation
negative regulation of gene expression, epigenetic
in utero embryonic development
humoral immune response
brain development
regulation of gene expression
hemopoiesis

Displaying **all 8** entries
GO Term
heterochromatin
nucleus
PcG protein complex
cytosol
ubiquitin ligase complex
nucleoplasm
nuclear body
PRC1 complex

Displaying **all 5** entries
GO Term
promoter-specific chromatin binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
zinc ion binding
RING-like zinc finger domain binding
ubiquitin-protein transferase activator activity

Annotation information from UniProt.

Sequence

MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKSSVNGSSATSSG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
255			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Oxidative Stress Induced Senescence	Homo sapiens
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Homo sapiens
Regulation of PTEN gene transcription	Homo sapiens
SUMOylation of DNA damage response and repair proteins	Homo sapiens
SUMOylation of DNA methylation proteins	Homo sapiens
SUMOylation of RNA binding proteins	Homo sapiens
SUMOylation of chromatin organization proteins	Homo sapiens
SUMOylation of transcription cofactors	Homo sapiens
Transcriptional Regulation by E2F6	Homo sapiens