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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
B-cell receptor CD22
Summary
- UniProt ID
- P35329
- Gene Symbol
-
- Cd22
- Lyb-8
- Siglec2
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003578
- GlyGen
- P35329
- PubChem
- P35329
Annotation
- Keyword
-
- Alternative splicing
- Cell adhesion
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Lectin
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| early endosome |
| external side of plasma membrane |
| cell surface |
| plasma membrane |
| recycling endosome |
| neuronal cell body membrane |
| GO Term |
|---|
| carbohydrate binding |
| coreceptor activity |
| protein phosphatase binding |
| sialic acid binding |
| CD4 receptor binding |
Sequence
MRVHYLWLLLILGHVASARYSSANDWTVDHPQTLFAWEGACIRIPCKYKTPLPKARLDNILLFQNYEFDKATKKFTGTVLYNATKTEKDPESELYLSKQGRVTFLGNRIDNCTLKIHPIRANDSGNLGLRMTAGTERWMEPIHLNVSEKPFQPYIQMPSEIRESQSVTLTCGLNFSCFGYDILLKWFLEDSEITSITSSVTSITSSVTSSIKNVYTESKLTFQPKWTDHGKSVKCQVQHSSKVLSERTVRLDVKYTPKLEIKVNPTEVEKNNSVTMTCRVNSSNPKLRTVAVSWFKDGRPLEDQELEQEQQMSKLILHSVTKDMRGKYRCQASNDIGPGESEEVELTVHYAPEPSRVHIYPSPAEEGQSVELICESLASPSATNYTWYHNRKPIPGDTQEKLRIPKVSPWHAGNYSCLAENRLGHGKIDQEAKLDVHYAPKAVTTVIQSFTPILEGDSVTLVCRYNSSNPDVTSYRWNPQGSGSVLKPGVLRIQKVTWDSMPVSCAACNHKCSWALPVILNVHYAPRDVKVLKVSPASEIRAGQRVLLQCDFAESNPAEVRFFWKKNGSLVQEGRYLSFGSVSPEDSGNYNCMVNNSIGETLSQAWNLQVLYAPRRLRVSISPGDHVMEGKKATLSCESDANPPISQYTWFDSSGQDLHSSGQKLRLEPLEVQHTGSYRCKGTNGIGTGESPPSTLTVYYSPETIGKRVALGLGFCLTICILAIWGMKIQKKWKQNRSQQGLQENSSGQSFFVRNKKARRTPLSEGPQSQGCYNPAMDDTVSYAILRFPESDTHNTGDAGTPATQAPPPNNSDSVTYSVIQKRPMGDYENVNPSCPEDESIHYSELVQFGAGKRPQAKEDVDYVTLKH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 111 | N-linked (GlcNAc...) asparagine | |||
| 122 | N-linked (GlcNAc...) asparagine | |||
| 145 | N-linked (GlcNAc...) asparagine |
|
||
| 174 | N-linked (GlcNAc...) asparagine |
|
||
| 271 | N-linked (GlcNAc...) asparagine | |||
| 281 | N-linked (GlcNAc...) asparagine |
|
||
| 384 | N-linked (GlcNAc...) asparagine |
|
||
| 408 |
|
|
||
| 414 | N-linked (GlcNAc...) asparagine | |||
| 466 | N-linked (GlcNAc...) asparagine |
G31852PQ
G39446WN
G86182NS
G27126ED
G15664MX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | Mus musculus |
| CD22 mediated BCR regulation | Mus musculus |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Mus musculus |
