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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Prostaglandin G/H synthase 2
Summary
- UniProt ID
- P35354
- Gene Symbol
-
- PTGS2
- COX2
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P35354
- PubChem
- P35354
- SwissLipids
- The Human Metabolome Database
- HMDBP00975
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Dioxygenase
- Disulfide bond
- Glycoprotein
- Heme
- Membrane
- Microsome
- Nucleus
- Peroxidase
- Prostaglandin biosynthesis
- Reference proteome
- S-nitrosylation
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| prostaglandin biosynthetic process |
| angiogenesis |
| response to oxidative stress |
| embryo implantation |
| memory |
| regulation of blood pressure |
| negative regulation of cell population proliferation |
| regulation of inflammatory response |
Sequence
MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 53 | N-linked (GlcNAc...) asparagine | |||
| 86 |
|
|
||
| 130 | N-linked (GlcNAc...) asparagine | |||
| 161 |
|
|
||
| 396 | N-linked (GlcNAc...) asparagine |
|
||
| 576 |
|
|
||
| 580 | N-linked (GlcNAc...) asparagine | |||
| 592 |
|
|
||
|
|
|
G46503DX
G01650EU
G23294PN
G25079LO
G48584BU
G70101JE
G80920RR
G64527OM
G62894KT
G62765YT
G05724UK
G31852PQ
G39188ZX
G41247ZX
G02815KT
G06110VR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Biosynthesis of DHA-derived SPMs | Homo sapiens |
| Biosynthesis of DPAn-3 SPMs | Homo sapiens |
| Biosynthesis of EPA-derived SPMs | Homo sapiens |
| Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives | Homo sapiens |
| Interleukin-10 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Nicotinamide salvaging | Homo sapiens |
| Synthesis of 15-eicosatetraenoic acid derivatives | Homo sapiens |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060643 | primary sclerosing cholangitis | |
| DOID:0060674 | catecholaminergic polymorphic ventricular tachycardia | |
| DOID:0060675 | catecholaminergic polymorphic ventricular tachycardia 1 | |
| DOID:0060676 | catecholaminergic polymorphic ventricular tachycardia 2 | |
| DOID:0060677 | catecholaminergic polymorphic ventricular tachycardia 3 | |
| DOID:0060678 | catecholaminergic polymorphic ventricular tachycardia 4 | |
| DOID:0060679 | catecholaminergic polymorphic ventricular tachycardia 5 | |
| DOID:0060700 | familial hypocalciuric hypercalcemia 1 | |
| DOID:0060731 | congenital central hypoventilation syndrome | |
| DOID:0060777 | congenital secretory sodium diarrhea 8 |
