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Cystathionine beta-synthase

Summary

UniProt ID

P35520

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlyGen: P35520
PubChem: P35520
The Human Metabolome Database: HMDBP00779
The O-GlcNAc Database: P35520

Annotation

Keyword

3D-structure
Allosteric enzyme
Alternative splicing
CBS domain
Cysteine biosynthesis
Cytoplasm
Disease variant
Heme
Isopeptide bond
Lyase
Nucleus
Phosphoprotein
Pyridoxal phosphate
Reference proteome
Ubl conjugation

Gene Ontology (GO)

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GO Term
endochondral ossification
blood vessel remodeling
superoxide metabolic process
maternal process involved in female pregnancy
cartilage development involved in endochondral bone morphogenesis
cerebellum morphogenesis
negative regulation of apoptotic process
cellular response to hypoxia
cysteine biosynthetic process via cystathionine
transsulfuration

Displaying **all 3** entries
GO Term
cytosol
cytoplasm
nucleus

Displaying entries **1 - 10** of 16 in total

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GO Term
enzyme binding
metal ion binding
oxygen binding
nitric oxide binding
modified amino acid binding
heme binding
pyridoxal phosphate binding
ubiquitin protein ligase binding
nitrite reductase (NO-forming) activity
identical protein binding

Annotation information from UniProt.

Sequence

MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFVAAQERDQK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites