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MIRAGE
Proto-oncogene tyrosine-protein kinase receptor Ret

Summary
UniProt ID
P35546
Gene Symbol
  • Ret
Gene ID
19713
Organism
Mus musculus (house mouse)
GlyGen
P35546
PubChem
P35546
Re-Glyco
P35546
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Alternative splicing
  • Calcium
  • Cell adhesion
  • Cell membrane
  • Disulfide bond
  • Endosome
  • Glycoprotein
  • Metal-binding
  • Phosphoprotein
  • Proto-oncogene
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
Gene Ontology (GO)
Displaying all 8 entries
GO Term
plasma membrane
axon
dendrite
neuronal cell body
receptor complex
plasma membrane protein complex
early endosome
endosome membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MAKATSGAAGLGLKLILLLPLLGEAPLGLYFSRDAYWERLYVDQPAGTPLLYVHALRDAPGEVPSFRLGQHLYGVYRTRLHENDWIRINETTGLLYLNQSLDHSSWEQLSIRNGGFPLLTIFLQVFLGSTAQREGECHWPGCTRVYFSFINDTFPNCSSFKAQDLCIPETAVSFRVRENRPPGTFYHFHMLPVQFLCPNISVKYSLLGGDSLPFRCDPDCLEVSTRWALDRELREKYVLEALCIVAGPGANKETVTLSFPVTVYDEDDSAPTFSGGVGTASAVVEFKRKEGTVVATLQVFDADVVPASGELVRRYTNTLLSGDSWAQQTFRVEHSPIETLVQVNNNSVRATMHNYKLILNRSLSISESRVLQLAVLVNDSDFQGPGAGGILVLHFNVSVLPVTLNLPRAYSFPVNKRARRYAQIGKVCVENCQEFSGVSIQYKLQPSSINCTALGVVTSPEDTSGTLFVNDTEALRRPECTKLQYTVVATDRQTRRQTQASLVVTVEGTSITEEVGCPKSCAVNKRRPECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTRTCPDGHCDAVESRDANICPQDCLRADIVGGHERGERQGIKAGYGICNCFPDEKKCFCEPEDSQGPLCDALCRTIITAALFSLIISILLSIFCVCHHHKHGHKPPIASAEMTFCRPAQGFPISYSSSGTRRPSLDSTENQVPVDSFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSGGGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKKSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTRADGTSTGFPRYANDSVYANWMVSPSAAKLMDTFDS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 15 in total
Position Description PubMed ID GlyTouCan ID Source
89 N-linked (GlcNAc...) asparagine
98 N-linked (GlcNAc...) asparagine
151 N-linked (GlcNAc...) asparagine
156 N-linked (GlcNAc...) asparagine
199 N-linked (GlcNAc...) asparagine
345 N-linked (GlcNAc...) asparagine
360 N-linked (GlcNAc...) asparagine
378 N-linked (GlcNAc...) asparagine
396 N-linked (GlcNAc...) asparagine
450 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
RAF/MAP kinase cascade Mus musculus
RET signaling Mus musculus
Disease
Displaying all 4 entries
DO ID Disease Name Source
DOID:0050771 pheochromocytoma
DOID:10016 multiple endocrine neoplasia type 2B
DOID:10487 Hirschsprung's disease
DOID:11836 clubfoot
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025