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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Sterol O-acyltransferase 1
Summary
- UniProt ID
- P35610
- Gene Symbol
-
- SOAT1
- ACACT
- ACACT1
- ACAT
- ACAT1
- SOAT
- STAT
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Acyltransferase
- Alternative splicing
- Cholesterol metabolism
- Disulfide bond
- Endoplasmic reticulum
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| membrane |
| GO Term |
|---|
| cholesterol binding |
| identical protein binding |
| fatty-acyl-CoA binding |
| sterol O-acyltransferase activity |
| cholesterol O-acyltransferase activity |
Sequence
MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 36 |
|
|||
| 38 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| LDL clearance | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080144 | childhood acute lymphocytic leukemia | |
| DOID:0080187 | chronic neutrophilic leukemia | |
| DOID:0080188 | chronic myelomonocytic leukemia | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080348 | Alzheimer's disease 1 | |
| DOID:0080409 | familial adenomatous polyposis 1 | |
| DOID:0090070 | hypogonadotropic hypogonadism | |
| DOID:0090071 | hypogonadotropic hypogonadism 11 with or without anosmia | |
| DOID:0090072 | hypogonadotropic hypogonadism 12 with or without anosmia | |
| DOID:0090073 | hypogonadotropic hypogonadism 13 with or without anosmia |
