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MIRAGE
Metalloproteinase inhibitor 3

Summary
UniProt ID
P35625
Gene Symbol
  • TIMP3
Gene ID
7078
Organism
Homo sapiens (human)
GlyGen
P35625
PubChem
P35625
Re-Glyco
P35625
Annotation
Keyword
  • 3D-structure
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Extracellular matrix
  • Metal-binding
  • Metalloprotease inhibitor
  • Reference proteome
  • Signal
  • Vision
  • Zinc
Gene Ontology (GO)
Displaying all 7 entries
GO Term
extracellular matrix
collagen-containing extracellular matrix
platelet dense granule lumen
extracellular region
basement membrane
extracellular space
nucleus
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNFVERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
207
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Platelet degranulation Homo sapiens
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:0090114 Sorsby's fundus dystrophy
DOID:11054 urinary bladder cancer
DOID:3459 breast carcinoma
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025