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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Perforin-1
Summary
- UniProt ID
- P35763
- Gene Symbol
-
- Prf1
- Pfp
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- P35763
Annotation
- Keyword
-
- Calcium
- Cell membrane
- Cytolysis
- Disulfide bond
- EGF-like domain
- Endosome
- Glycoprotein
- Lysosome
- Metal-binding
- Reference proteome
- Secreted
- Signal
- Transmembrane beta strand
- Gene Ontology (GO)
| GO Term |
|---|
| protein import |
| defense response to virus |
| granzyme-mediated programmed cell death signaling pathway |
| protein homooligomerization |
| GO Term |
|---|
| membrane |
| extracellular space |
| plasma membrane |
| cytoplasmic vesicle |
| endosome lumen |
| cytolytic granule |
| immunological synapse |
| GO Term |
|---|
| calcium ion binding |
| identical protein binding |
| wide pore channel activity |
| pore-forming activity |
Sequence
MAAYLFLLGLFLLLPRPVPAPCYTATRSECKQNHKFVPGVWAAGEGVDVTTLRRSSSFPVNTGKFLRPDRTCTLCKNALMNDGIQRLPVAIAHWRPHGSHCQRNVATTKVSSTEGVAREAAANINNDWRAGLDVNPKPEANVHVSVAGSHSKIANFAAEKAHQDQYNFNTDTVECRMYSFRLAQKPPLHPDFRKALKNLPHNFNSSTEHAYRRLISSYGTHFITAVDLGGRVSVLTALRTCQLTLDGLTADEVGDCLSVEAQVSIGAQASVSSEYKACEEKKKQHKIATSFHQTYRERHVEVLGGPLDSSNDLLFGNQATPEHFSTWIASLPTRPDVVDYSLEPLHILLEDSDPKREALRQAISHYVMSRARWRDCNRPCRAGQHKSSRDSCQCVCQDSNVTNQDCCPRQRGLAKLMVRNFQAKGLWGDYITSTDAYLKVFFGGQEIRTGVVWNNNHPSWSDKMDFGNVLLSTGGPLRVQVWDADNGWDDDLLGTCDKSPKSGFHEVNCPLNHGSIKFIYQANCLPDLTGETCLEYAPQGLLGDPRGNRSGAVW
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
