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Fragile X messenger ribonucleoprotein 1

Summary

UniProt ID

P35922

Gene Symbol

Fmr1
Fmr-1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P35922
The O-GlcNAc Database: P35922

Annotation

Keyword

Acetylation
Activator
Alternative splicing
Cell membrane
Cell projection
Centromere
Chromosome
Cytoplasm
DNA damage
Methylation
Neurogenesis
Nucleus
Phosphoprotein
Postsynaptic cell membrane
RNA-binding
RNA-mediated gene silencing
Reference proteome
Repeat
Repressor
Ribonucleoprotein
Synaptosome
Translation regulation
Ubl conjugation
mRNA splicing
mRNA transport

Gene Ontology (GO)

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GO Term
positive regulation of protein phosphorylation
glutamate receptor signaling pathway
central nervous system development
anterograde axonal transport
positive regulation of gene expression
negative regulation of gene expression
transmission of nerve impulse
regulation of neurotransmitter secretion
animal organ development
positive regulation of synaptic transmission

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GO Term
postsynaptic membrane
presynapse
axon cytoplasm
dendrite
neuronal cell body
axon terminus
cell body
glial cell projection
postsynapse
glutamatergic synapse

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GO Term
chromatin binding
RNA binding
microtubule binding
protein kinase binding
translation regulator activity
N6-methyladenosine-containing RNA reader activity
sequence-specific mRNA binding
protein domain specific binding
protein homodimerization activity
protein heterodimerization activity

Annotation information from UniProt.

Sequence

MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPERQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLEVPEDLRQMCAKESAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLILRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKSVPQEEEIMPPSSLPSNNSRVGPNSSEEKKHLDTKENTHFSQPNSTKVQRVLVVSSIVAGGPQKPEPKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKGYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRRGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTADGSLQSASSEGSRLRTGKDRNQKKEKPDSVDGLQPLVNGVP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites