Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

Summary
UniProt ID
P36551
Gene Symbol
  • CPO
  • CPOX
  • CPX
Gene ID
1371
Organism
Homo sapiens (human)
GlyGen
P36551
PubChem
P36551
The Human Metabolome Database
HMDBP00251
Re-Glyco
P36551
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Disease variant
  • Heme biosynthesis
  • Hereditary hemolytic anemia
  • Mitochondrion
  • Oxidoreductase
  • Phosphoprotein
  • Porphyrin biosynthesis
  • Reference proteome
  • Transit peptide
Gene Ontology (GO)
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Sequence
MALQLGRLSSGPCWLVARGGCGGPRAWSQCGGGGLRAWSQRSAAGRVCRPPGPAGTEQSRGLGHGSTSRGGPWVGTGLAAALAGLVGLATAAFGHVQRAEMLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRRPGDMKTKMELLILETQAQVCQALAQVDGGANFSVDRWERKEGGGGISCVLQDGCVFEKAGVSISVVHGNLSEEAAKQMRSRGKVLKTKDGKLPFCAMGVSSVIHPKNPHAPTIHFNYRYFEVEEADGNKQWWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDLYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEVFRFVQSCARAVVPSYIPLVKKHCDDSFTPQEKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPSENSKEAEILEVLRHPRDWVR
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
213
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Heme biosynthesis Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:13269 hereditary coproporphyria
DOID:409 liver disease

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025