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MIRAGE
Tumor necrosis factor ligand superfamily member 6
Summary
- UniProt ID
- P36940
- Gene Symbol
-
- Apt1Lg1
- Cd95l
- Fasl
- Faslg
- Tnfsf6
- Gene ID
- 25385
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Apoptosis
- Cell membrane
- Cytokine
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Lysosome
- Nucleus
- Reference proteome
- Repressor
- Secreted
- Signal-anchor
- Transcription regulation
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytokine activity |
| tumor necrosis factor receptor binding |
| death receptor binding |
Sequence
MQQPVNYPCPQIYWVDSSATSPWAPPGSVFSCPSSGPRGPGQRRPPPPPPPPSPLPPPSQPPPLPPLSPLKKKDNIELWLPVIFFMVLVALVGMGLGMYQLFHLQKELAELREFTNHSLRVSSFEKQIANPSTPSETKKPRSVAHLTGNPRSRSIPLEWEDTYGTALISGVKYKKGGLVINEAGLYFVYSKVYFRGQSCNSQPLSHKVYMRNFKYPGDLVLMEEKKLNYCTTGQIWAHSSYLGAVFNLTVADHLYVNISQLSLINFEESKTFFGLYKL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CASP8 activity is inhibited | Rattus norvegicus |
| Dimerization of procaspase-8 | Rattus norvegicus |
| FasL/ CD95L signaling | Rattus norvegicus |
| Regulation by c-FLIP | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060108 | brain glioma | |
| DOID:303 | substance-related disorder | |
| DOID:9744 | type 1 diabetes mellitus |
