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Thrombopoietin

Summary

UniProt ID

P40226

Gene Symbol

Thpo

Organism

Mus musculus (house mouse)

External Links

PubChem: P40226

Annotation

Keyword

3D-structure
Alternative splicing
Cytokine
Disulfide bond
Glycoprotein
Hormone
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
positive regulation of protein phosphorylation
cell population proliferation
myeloid cell differentiation
megakaryocyte differentiation
positive regulation of megakaryocyte differentiation
positive regulation of hematopoietic stem cell proliferation
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
thrombopoietin-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade

Displaying **all 2** entries
GO Term
extracellular region
extracellular space

Displaying **all 3** entries
GO Term
signaling receptor binding
cytokine activity
hormone activity

Annotation information from UniProt.

Sequence

MELTDLLLAAMLLAVARLTLSSPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDGHTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQET

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
197	N-linked (GlcNAc...) asparagine	UniProt
206	N-linked (GlcNAc...) asparagine	UniProt
235	N-linked (GlcNAc...) asparagine	UniProt
249	N-linked (GlcNAc...) asparagine	UniProt
256	N-linked (GlcNAc...) asparagine	UniProt
336	N-linked (GlcNAc...) asparagine	UniProt
351	N-linked (GlcNAc...) asparagine	UniProt