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Thrombopoietin

Summary

UniProt ID

P40226

Gene Symbol

Thpo

Organism

Mus musculus (house mouse)

External Links

PubChem: P40226

Annotation

Keyword

3D-structure
Alternative splicing
Cytokine
Disulfide bond
Glycoprotein
Hormone
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
positive regulation of ERK1 and ERK2 cascade
cell population proliferation
myeloid cell differentiation
megakaryocyte differentiation
positive regulation of megakaryocyte differentiation
positive regulation of hematopoietic stem cell proliferation
thrombopoietin-mediated signaling pathway
positive regulation of protein phosphorylation

Displaying **all 2** entries
GO Term
extracellular region
extracellular space

Displaying **all 3** entries
GO Term
signaling receptor binding
cytokine activity
hormone activity

Annotation information from UniProt.

Sequence

MELTDLLLAAMLLAVARLTLSSPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDGHTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQET

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	Source
197	N-linked (GlcNAc...) asparagine	UniProt
206	N-linked (GlcNAc...) asparagine	UniProt
235	N-linked (GlcNAc...) asparagine	UniProt
249	N-linked (GlcNAc...) asparagine	UniProt
256	N-linked (GlcNAc...) asparagine	UniProt
336	N-linked (GlcNAc...) asparagine	UniProt
351	N-linked (GlcNAc...) asparagine	UniProt