Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Malate dehydrogenase, mitochondrial
Summary
- UniProt ID
- P40926
- Gene Symbol
-
- MDH2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Disease variant
- Epilepsy
- Glycoprotein
- Mitochondrion
- NAD
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Transit peptide
- Tricarboxylic acid cycle
- Gene Ontology (GO)
| GO Term |
|---|
| gluconeogenesis |
| tricarboxylic acid cycle |
| aerobic respiration |
| oxaloacetate metabolic process |
| malate metabolic process |
| NADH metabolic process |
| GO Term |
|---|
| nucleus |
| cytoplasm |
| membrane |
| extracellular exosome |
| mitochondrion |
| mitochondrial matrix |
| cytosol |
| GO Term |
|---|
| L-malate dehydrogenase activity |
| malate dehydrogenase (NADP+) activity |
| RNA binding |
| protein self-association |
Sequence
MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
Glycosylation Sites
G49108TO
G70994MS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Citric acid cycle (TCA cycle) | Homo sapiens |
| Malate-aspartate shuttle | Homo sapiens |
| Mitochondrial protein degradation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110043 | Alzheimer's disease 10 | |
| DOID:0110044 | Alzheimer's disease 11 | |
| DOID:0110045 | Alzheimer's disease 12 | |
| DOID:0110046 | Alzheimer's disease 13 | |
| DOID:0110047 | Alzheimer's disease 14 | |
| DOID:0110048 | Alzheimer's disease 15 | |
| DOID:10021 | duodenum cancer | |
| DOID:10154 | small intestine cancer | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma |
