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MIRAGE
Glutamate receptor 1

Summary
UniProt ID
P42261
Gene Symbol
  • GLUA1
  • GLUH1
  • GLUR1
  • GRIA1
Gene ID
2890
Organism
Homo sapiens (human)
GlyGen
P42261
PubChem
P42261
The Human Metabolome Database
HMDBP02795
The O-GlcNAc Database
P42261
O-GlcNAcAtlas
P42261
Re-Glyco
P42261
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Cell projection
  • Disease variant
  • Disulfide bond
  • Endoplasmic reticulum
  • Endosome
  • Glycoprotein
  • Intellectual disability
  • Ligand-gated ion channel
  • Palmitate
  • Phosphoprotein
  • Postsynaptic cell membrane
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Annotation information from UniProt.
Sequence
MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMPLGATGL
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
63 N-linked (GlcNAc...) asparagine
249 N-linked (GlcNAc...) asparagine
257 N-linked (GlcNAc...) asparagine
362
363 N-linked (GlcNAc...) asparagine
401 N-linked (GlcNAc...) asparagine
406 N-linked (GlcNAc...) asparagine
849
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 8 entries
Pathway Name Organism
Activation of AMPA receptors Homo sapiens
COPII-mediated vesicle transport Homo sapiens
Cargo concentration in the ER Homo sapiens
Long-term potentiation Homo sapiens
Synaptic adhesion-like molecules Homo sapiens
Trafficking of AMPA receptors Homo sapiens
Trafficking of GluR2-containing AMPA receptors Homo sapiens
Unblocking of NMDA receptors, glutamate binding and activation Homo sapiens
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:0060307 autosomal dominant intellectual developmental disorder
DOID:0081235 autosomal recessive intellectual developmental disorder 76
DOID:1826 epilepsy
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025