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MIRAGE
Glutamate receptor 3

Summary
UniProt ID
P42263
Gene Symbol
  • GLUR3
  • GLURC
  • GRIA3
  • GluA3
Gene ID
2892
Organism
Homo sapiens (human)
PubChem
P42263
The Human Metabolome Database
HMDBP12049
Re-Glyco
P42263
Annotation
Keyword
  • Alternative splicing
  • Cell membrane
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Intellectual disability
  • Ligand-gated ion channel
  • Palmitate
  • Phosphoprotein
  • Postsynaptic cell membrane
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 7 entries
GO Term
AMPA glutamate receptor complex
parallel fiber to Purkinje cell synapse
postsynaptic membrane
endocytic vesicle membrane
dendritic spine
postsynaptic density membrane
plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MARQKKMGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSASSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
63 N-linked (GlcNAc...) asparagine
266 N-linked (GlcNAc...) asparagine
380 N-linked (GlcNAc...) asparagine
415 N-linked (GlcNAc...) asparagine
422 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
Activation of AMPA receptors Homo sapiens
Synaptic adhesion-like molecules Homo sapiens
Trafficking of AMPA receptors Homo sapiens
Trafficking of GluR2-containing AMPA receptors Homo sapiens
Unblocking of NMDA receptors, glutamate binding and activation Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0060823 syndromic X-linked intellectual disability 94
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025