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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Summary
- UniProt ID
- P42338
- Gene Symbol
-
- PIK3CB
- PIK3C1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P42338
- PubChem
- P42338
- The Human Metabolome Database
- HMDBP01208
- The O-GlcNAc Database
- P42338
Annotation
- Keyword
-
- ATP-binding
- Autophagy
- Cell adhesion
- Cytoplasm
- Endocytosis
- Kinase
- Lipid metabolism
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| regulation of cell-matrix adhesion |
| response to ischemia |
| sphingosine-1-phosphate receptor signaling pathway |
Sequence
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEHEPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDEVSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 478 |
|
|||
| 481 |
|
|||
| 485 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PI3K Cascade | Homo sapiens |
| PI3K/AKT Signaling | Homo sapiens |
| PI3K/AKT activation | Homo sapiens |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| RET signaling | Homo sapiens |
| Regulation of signaling by CBL | Homo sapiens |
| Role of LAT2/NTAL/LAB on calcium mobilization | Homo sapiens |
| Role of phospholipids in phagocytosis | Homo sapiens |
| Signaling by ALK | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070329 | mitochondrial DNA depletion syndrome | |
| DOID:0080001 | bone disease | |
| DOID:0080144 | childhood acute lymphocytic leukemia | |
| DOID:0080145 | childhood T-cell acute lymphoblastic leukemia | |
| DOID:0080146 | childhood B-cell acute lymphoblastic leukemia | |
| DOID:0080147 | lymphoblastic lymphoma | |
| DOID:0080149 | adult acute monocytic leukemia | |
| DOID:0080158 | herpes simplex virus keratitis | |
| DOID:0080162 | lupus nephritis | |
| DOID:0080191 | PTEN hamartoma tumor syndrome |
