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Leukemia inhibitory factor receptor

Summary

UniProt ID

P42702

Gene Symbol

LIFR

Organism

Homo sapiens (human)

External Links

GlyGen: P42702
PubChem: P42702
The O-GlcNAc Database: P42702
O-GlcNAcAtlas: P42702

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Chromosomal rearrangement
Disease variant
Disulfide bond
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
cell surface receptor signaling pathway
positive regulation of cell population proliferation
cytokine-mediated signaling pathway
response to cytokine
oncostatin-M-mediated signaling pathway
leukemia inhibitory factor signaling pathway
ciliary neurotrophic factor-mediated signaling pathway

Displaying **all 4** entries
GO Term
plasma membrane
receptor complex
external side of plasma membrane
extracellular exosome

Displaying **all 5** entries
GO Term
growth factor binding
cytokine binding
leukemia inhibitory factor receptor activity
cytokine receptor activity
ciliary neurotrophic factor receptor binding

Annotation information from UniProt.

Sequence

MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSPVKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIKIRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPDTWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEMNPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPNPAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEEDLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKSNGGGWSFTNFFQNKPND

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 22 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
64	N-linked (GlcNAc...) asparagine		G80920RR G62765YT G31852PQ	UniProt GlyGen
85	N-linked (GlcNAc...) asparagine		G80920RR	UniProt GlyGen
131	N-linked (GlcNAc...) asparagine	18775332		UniProt GlyGen
143	N-linked (GlcNAc...) asparagine			UniProt GlyGen
191	N-linked (GlcNAc...) asparagine		G76535FN	UniProt GlyGen
243	N-linked (GlcNAc...) asparagine		G46503DX	UniProt GlyGen
245			G49108TO	GlyGen The O-GlcNAc Database
303	N-linked (GlcNAc...) asparagine	18775332		UniProt GlyGen
390	N-linked (GlcNAc...) asparagine			UniProt GlyGen
407	N-linked (GlcNAc...) asparagine	18775332		UniProt GlyGen