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MIRAGE
Endothelin-converting enzyme 1
Summary
- UniProt ID
- P42893
- Gene Symbol
-
- Ece1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| membrane |
| secretory granule |
| vesicle |
| endosome |
| early endosome |
| external side of plasma membrane |
| perinuclear region of cytoplasm |
| Weibel-Palade body |
| GO Term |
|---|
| zinc ion binding |
| endopeptidase activity |
| metalloendopeptidase activity |
| identical protein binding |
| protein homodimerization activity |
Sequence
MGSLRPPQGLGLQWSSFFLGKKGPGLTVSLPLLASSLQVNFRSPRSGQRCWAARTSVEKRLVVLVTLLAAGLVACLAALGIQYRTRTPPVCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTASASEAEKKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEDSIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNAIFYPVEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIILEIKKAFEESLSTLKWMDEDTRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSLRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYNNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQILPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPLGSPMNPRHKCEVW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 158 | N-linked (GlcNAc...) asparagine |
|
||
| 179 | N-linked (GlcNAc...) asparagine |
|
||
| 202 | N-linked (GlcNAc...) asparagine |
|
||
| 262 | N-linked (GlcNAc...) asparagine |
|
||
| 308 | N-linked (GlcNAc...) asparagine |
|
||
| 354 | N-linked (GlcNAc...) asparagine |
|
||
| 375 | N-linked (GlcNAc...) asparagine |
|
||
| 531 | N-linked (GlcNAc...) asparagine |
|
||
| 624 | N-linked (GlcNAc...) asparagine |
|
||
| 643 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Peptide ligand-binding receptors | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10763 | hypertension | |
| DOID:3021 | acute kidney failure | |
| DOID:6000 | congestive heart failure | |
| DOID:6432 | pulmonary hypertension | |
| DOID:9279 | hyperhomocysteinemia |
