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MIRAGE
Excitatory amino acid transporter 1
Summary
- UniProt ID
- P43003
- Gene Symbol
-
- EAAT1
- GLAST
- GLAST1
- SLC1A3
- Gene ID
- 6507
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P43003
- PubChem
- P43003
- The Human Metabolome Database
- HMDBP03133
- Re-Glyco
- P43003
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Amino-acid transport
- Cell membrane
- Chloride
- Disease variant
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Potassium
- Reference proteome
- Sodium
- Symport
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasmic vesicle |
| neuron projection |
| neuronal cell body |
| synapse |
| membrane protein complex |
| basal plasma membrane |
| cell surface |
| perinuclear region of cytoplasm |
| plasma membrane |
| membrane |
Sequence
MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
Glycosylation Sites
G20706XG
G64409MC
G11101UV
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | Homo sapiens |
| Defective SLC1A3 causes episodic ataxia 6 (EA6) | Homo sapiens |
| Glutamate Neurotransmitter Release Cycle | Homo sapiens |
| Transport of inorganic cations/anions and amino acids/oligopeptides | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050994 | episodic ataxia type 6 |
