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DNA mismatch repair protein Msh2

Summary

UniProt ID

P43247

Gene Symbol

Msh2

Organism

Mus musculus (house mouse)

External Links

GlyGen: P43247
PubChem: P43247
The O-GlcNAc Database: P43247

Annotation

Keyword

ATP-binding
Acetylation
Cell cycle
Chromosome
DNA repair
DNA-binding
Nucleus
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying entries **21 - 29** of 29 in total

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GO Term
B cell mediated immunity
B cell differentiation
isotype switching
regulation of cell cycle
negative regulation of neuron apoptotic process
negative regulation of DNA recombination
protein localization to chromatin
mitotic intra-S DNA damage checkpoint signaling
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Displaying **all 5** entries
GO Term
MutSalpha complex
MutSbeta complex
nucleus
chromosome
nucleoplasm

Displaying entries **11 - 19** of 19 in total

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GO Term
dinucleotide repeat insertion binding
oxidized purine DNA binding
MutLalpha complex binding
ATP-dependent DNA damage sensor activity
DNA binding
chromatin binding
centromeric DNA binding
mismatched DNA binding
protein homodimerization activity

Annotation information from UniProt.

Sequence

MAVQPKETLQLEGAAEAGFVRFFEGMPEKPSTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGPAGSKTLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNKAGNKASKENEWYLAFKASPGNLSQFEDILFGNNDMSASVGVMGIKMAVVDGQRHVGVGYVDSTQRKLGLCEFPENDQFSNLEALLIQIGPKECVLPGGETTGDMGKLRQVIQRGGILITERKRADFSTKDIYQDLNRLLKGKKGEQINSAALPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELATFDFSQYMKLDMAAVRALNLFQGSVEDTTGSQSLAALLNKCKTAQGQRLVNQWIKQPLMDRNRIEERLNLVEAFVEDSELRQSLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPSVIQALEKYEGRHQALLLAVFVTPLIDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSELREVMDGLEKKMQSTLINAARGLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSELSSLNEEYTKNKGEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAHLDAIVSFAHVSNAAPVPYVRPVILEKGKGRIILKASRHACVEVQDEVAFIPNDVHFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISDYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPRHVIACAKQKALELEEFQNIGTSLGCDEAEPAAKRRCLEREQGEKIILEFLSKVKQVPFTAMSEESISAKLKQLKAEVVAKNNSFVNEIISRIKAPAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites