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RAC-alpha serine/threonine-protein kinase
Summary
- UniProt ID
- P47196
- Gene Symbol
-
- Akt1
- Organism
- Rattus norvegicus (Norway rat)
External Links
- GlyGen
- P47196
- PubChem
- P47196
- The Human Metabolome Database
- HMDBP13421
- The O-GlcNAc Database
- P47196
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Apoptosis
- Cell membrane
- Cytoplasm
- Developmental protein
- Disulfide bond
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Glycoprotein
- Isopeptide bond
- Mitochondrion
- Neurogenesis
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Sugar transport
- Translation regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| plasma membrane |
| cell-cell junction |
| membrane |
| protein-containing complex |
| vesicle |
| glutamatergic synapse |
| mitochondrion |
| cytosol |
Sequence
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDFRSGSPSDNSGAEEMEVALAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 126 | O-linked (GlcNAc) serine; alternate |
|
||
| 129 | O-linked (GlcNAc) serine; alternate |
|
||
| 305 | O-linked (GlcNAc) threonine |
|
||
| 312 | O-linked (GlcNAc) threonine |
|
||
| 473 | O-linked (GlcNAc) serine; alternate |
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PI3K/AKT Signaling | Rattus norvegicus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Rattus norvegicus |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | Rattus norvegicus |
| RAB GEFs exchange GTP for GDP on RABs | Rattus norvegicus |
| Regulation of PTEN stability and activity | Rattus norvegicus |
| Regulation of TP53 Activity through Acetylation | Rattus norvegicus |
| Regulation of TP53 Activity through Association with Co-factors | Rattus norvegicus |
| Regulation of TP53 Degradation | Rattus norvegicus |
| Regulation of localization of FOXO transcription factors | Rattus norvegicus |
| TP53 Regulates Metabolic Genes | Rattus norvegicus |
