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Cytosolic phospholipase A2

Summary

UniProt ID

P47712

Gene Symbol

CPLA2
PLA2G4
PLA2G4A

Gene ID

5321

Organism

Homo sapiens (human)

External Links

PubChem

P47712

SwissLipids

SLP:000000565

The Human Metabolome Database

HMDBP00060

The O-GlcNAc Database

P47712

Re-Glyco

P47712

Annotation

Keyword

3D-structure
Calcium
Cytoplasm
Direct protein sequencing
Disease variant
Glycerol metabolism
Golgi apparatus
Hydrolase
Isopeptide bond
Leukotriene biosynthesis
Lipid-binding
Membrane
Metal-binding
Nucleus
Phospholipid degradation
Phosphoprotein
Prostaglandin biosynthesis
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
nucleus
nuclear envelope
cytoplasm
mitochondrial inner membrane
intracellular membrane-bounded organelle
Golgi membrane
endoplasmic reticulum
endoplasmic reticulum membrane
Golgi apparatus
cytosol

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 19 in total

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GO Term
arachidonic acid metabolic process
arachidonic acid secretion
cellular response to antibiotic
glycerol metabolic process
platelet activating factor biosynthetic process
positive regulation of prostaglandin secretion
phosphatidylcholine catabolic process
positive regulation of macrophage activation
glycerophospholipid catabolic process
icosanoid metabolic process

Displaying entries **1 - 10** of 11 in total

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2

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GO Term
O-acyltransferase activity
calcium ion binding
calcium-independent phospholipase A2 activity
calcium-dependent phospholipid binding
phosphatidylinositol-3-phosphate binding
lysophospholipase activity
phospholipase A2 activity
phosphatidylinositol-5-phosphate binding
calcium-dependent phospholipase A2 activity
phosphatidylinositol-4-phosphate binding

Annotation information from UniProt.

Sequence

MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETEEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRRQNPSRCSVSLSNVEARRFFNKEFLSKPKA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites