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Extracellular calcium-sensing receptor

Summary

UniProt ID

P48442

Gene Symbol

Casr
Gprc2a
Pcar1

Gene ID

24247

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P48442
Re-Glyco: P48442

Annotation

Keyword

Calcium
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
plasma membrane
axon
neuronal cell body
cell surface
basolateral plasma membrane
apical plasma membrane
presynaptic membrane
axon terminus
glutamatergic synapse

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 33 in total

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GO Term
ossification
intracellular calcium ion homeostasis
G protein-coupled receptor signaling pathway
positive regulation of cell population proliferation
positive regulation of gene expression
positive regulation of insulin secretion
bile acid secretion
branching morphogenesis of an epithelial tube
positive regulation of vasoconstriction
cellular response to low-density lipoprotein particle stimulus

Displaying **all 7** entries
GO Term
integrin binding
amino acid binding
protein kinase binding
protein homodimerization activity
transmembrane transporter binding
G protein-coupled receptor activity
calcium ion binding

Annotation information from UniProt.

Sequence

MASYSCCLALLALAWHSSAYGPDQRAQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRYNFRGFRWLQAMIFAIEEINSSPSLLPNMTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQYKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQQVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGRIWLASEAWASSSLIAMPEYFHVVGGTIGFGLKAGQIPGFREFLQKVHPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFVRSHEEGGNRLLNSSTAFRPLCTGDENINSVETPYMDYEHLRISYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFSREVPFSNCSRDCQAGTRKGIIEGEPTCCFECVECPDGEYSGETDASACDKCPDDFWSNENHTSCIAKEIEFLAWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQILICIIWLYTAPPSSYRNHELEDEIIFITCHEGSLMALGSLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTYGKFVSAVEVIAILAASFGLLACIFFNKVYIILFKPSRNTIEEVRSSTAAHAFKVAARATLRRPNISRKRSSSLGGSTGSIPSSSISSKSNSEDRFPQPERQKQQQPLSLTQQEQQQQPLTLHPQQQQQPQQPRCKQKVIFGSGTVTFSLSFDEPQKNAMAHRNSMRQNSLEAQRSNDTLGRHQALLPLQCADADSEMTIQETGLQGPMVGDHQPEMESSDEMSPALVMSTSRSFVISGGGSSVTENVLHS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	Source
90	N-linked (GlcNAc...) asparagine	UniProt
130	N-linked (GlcNAc...) asparagine	UniProt
261	N-linked (GlcNAc...) asparagine	UniProt
287	N-linked (GlcNAc...) asparagine	UniProt
386	N-linked (GlcNAc...) asparagine	UniProt
446	N-linked (GlcNAc...) asparagine	UniProt
468	N-linked (GlcNAc...) asparagine	UniProt
488	N-linked (GlcNAc...) asparagine	UniProt
541	N-linked (GlcNAc...) asparagine	UniProt
594	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Class C/3 (Metabotropic glutamate/pheromone receptors)	Rattus norvegicus
G alpha (i) signalling events	Rattus norvegicus
G alpha (q) signalling events	Rattus norvegicus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050700	cardiomyopathy	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

Annotation

International Collaboration

Acknowledgements