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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Protein ERGIC-53
Summary
- UniProt ID
- P49257
- Gene Symbol
-
- LMAN1
- ERGIC53
- F5F8D
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Disulfide bond
- ER-Golgi transport
- Endoplasmic reticulum
- Golgi apparatus
- Lectin
- Metal-binding
- Phosphoprotein
- Protein transport
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| metal ion binding |
| unfolded protein binding |
| mannose binding |
Sequence
MAGSRQRGLRARVRPLFCALLLSLGRFVRGDGVGGDPAVALPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSSDQIRVAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGADGLAIWYAENQGLEGPVFGSADLWNGVGIFFDSFDNDGKKNNPAIVIIGNNGQIHYDHQNDGASQALASCQRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPAQGHFGISAATGGLADDHDVLSFLTFQLTEPGKEPPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPAEEIFESVGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISKRGAGMPGQHGQITQQELDTVVKTQHEILRQVNEMKNSMSETVRLVSGMQHPGSAGGVYETTQHFIDIKEHLHIVKRDIDNLVQRNMPSNEKPKCPELPPFPSCLSTVHFIIFVVVQTVLFIGYIMYRSQQEAAAKKFF
Glycosylation Sites
G53434XO
G57321FI
G43417UB
G29068FM
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| COPII-mediated vesicle transport | Homo sapiens |
| Cargo concentration in the ER | Homo sapiens |
| RAC2 GTPase cycle | Homo sapiens |
| RAC3 GTPase cycle | Homo sapiens |
| RHOA GTPase cycle | Homo sapiens |
| RHOC GTPase cycle | Homo sapiens |
| RHOD GTPase cycle | Homo sapiens |
| RHOG GTPase cycle | Homo sapiens |
| Transport to the Golgi and subsequent modification | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111401 | congenital dyserythropoietic anemia type II | |
| DOID:11249 | vitamin K deficiency bleeding | |
| DOID:1205 | allergic disease | |
| DOID:12134 | factor VIII deficiency | |
| DOID:12365 | malaria | |
| DOID:1247 | blood coagulation disease | |
| DOID:1338 | congenital dyserythropoietic anemia | |
| DOID:13481 | thanatophoric dysplasia | |
| DOID:13739 | nutmeg liver | |
| DOID:162 | cancer |
