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Inositol polyphosphate 1-phosphatase
Summary
- UniProt ID
- P49441
- Gene Symbol
-
- INPP1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P49441
- PubChem
- P49441
- The Human Metabolome Database
- HMDBP00362
- The O-GlcNAc Database
- P49441
Annotation
- Keyword
-
- Hydrolase
- Lithium
- Magnesium
- Metal-binding
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| phosphate-containing compound metabolic process |
| signal transduction |
| phosphatidylinositol phosphate biosynthetic process |
| GO Term |
|---|
| cytosol |
| GO Term |
|---|
| metal ion binding |
| inositol-1,3,4-trisphosphate 1-phosphatase activity |
| inositol-1,4-bisphosphate 1-phosphatase activity |
Sequence
MSDILRELLCVSEKAANIARACRQQEALFQLLIEEKKEGEKNKKFAVDFKTLADVLVQEVIKQNMENKFPGLEKNIFGEESNEFTNDWGEKITLRLCSTEEETAELLSKVLNGNKVASEALARVVHQDVAFTDPTLDSTEINVPQDILGIWVDPIDSTYQYIKGSADIKSNQGIFPCGLQCVTILIGVYDIQTGVPLMGVINQPFVSRDPNTLRWKGQCYWGLSYMGTNMHSLQLTISRRNGSETHTGNTGSEAAFSPSFSAVISTSEKETIKAALSRVCGDRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKWDSCAAHAILRAMGGGIVDLKECLERNPETGLDLPQLVYHVENEGAAGVDRWANKGGLIAYRSRKRLETFLSLLVQNLAPAETHT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Synthesis of IP2, IP, and Ins in the cytosol | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080221 | obsolete major affective disorder 2 | |
| DOID:162 | cancer | |
| DOID:3312 | bipolar disorder | |
| DOID:4766 | embryoma | |
| DOID:5672 | large intestine cancer | |
| DOID:9256 | colorectal cancer |
