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P2X purinoceptor 2

Summary

UniProt ID

P49653

Gene Symbol

P2rx2

Gene ID

114115

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P49653
PubChem: P49653
Re-Glyco: P49653

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Ligand-gated ion channel
Receptor
Reference proteome
Transmembrane helix

Gene Ontology (GO)

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GO Term
Schaffer collateral - CA1 synapse
glutamatergic synapse
neuronal dense core vesicle
parallel fiber to Purkinje cell synapse
plasma membrane
neuronal cell body
receptor complex
cell surface
apical plasma membrane
presynaptic membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
regulation of presynaptic cytosolic calcium ion concentration
response to ischemia
detection of hypoxic conditions in blood by carotid body chemoreceptor signaling
response to carbohydrate
neuronal action potential
response to ATP
behavioral response to pain
skeletal muscle fiber development
calcium ion transmembrane transport
response to organic cyclic compound

Displaying entries **1 - 10** of 14 in total

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GO Term
zinc ion binding
mercury ion binding
cadmium ion binding
cobalt ion binding
purinergic nucleotide receptor activity
extracellularly ATP-gated monoatomic cation channel activity
copper ion binding
ATP binding
ligand-gated monoatomic ion channel activity
phosphatidylinositol binding

Annotation information from UniProt.

Sequence

MVRRLARGCWSAFWDYETPKVIVVRNRRLGFVHRMVQLLILLYFVWYVFIVQKSYQDSETGPESSIITKVKGITMSEDKVWDVEEYVKPPEGGSVVSIITRIEVTPSQTLGTCPESMRVHSSTCHSDDDCIAGQLDMQGNGIRTGHCVPYYHGDSKTCEVSAWCPVEDGTSDNHFLGKMAPNFTILIKNSIHYPKFKFSKGNIASQKSDYLKHCTFDQDSDPYCPIFRLGFIVEKAGENFTELAHKGGVIGVIINWNCDLDLSESECNPKYSFRRLDPKYDPASSGYNFRFAKYYKINGTTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSIGVGSFLCDWILLTFMNKNKLYSHKKFDKVRTPKHPSSRWPVTLALVLGQIPPPPSHYSQDQPPSPPSGEGPTLGEGAELPLAVQSPRPCSISALTEQVVDTLGQHMGQRPPVPEPSQQDSTSTDPKGLAQL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
182	N-linked (GlcNAc...) asparagine	UniProt GlyGen
239	N-linked (GlcNAc...) asparagine	UniProt GlyGen
298	N-linked (GlcNAc...) asparagine	UniProt GlyGen
413		GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Elevation of cytosolic Ca2+ levels	Rattus norvegicus
Platelet homeostasis	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

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International Collaboration

Acknowledgements