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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Estrogen receptor
Summary
- UniProt ID
- P49884
- Gene Symbol
-
- ESR1
- ESR
- NR3A1
- Organism
- Bos taurus (domestic cattle)
Annotation
- Keyword
-
- Activator
- Cell membrane
- Cytoplasm
- DNA-binding
- Glycoprotein
- Golgi apparatus
- Methylation
- Nucleus
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Steroid-binding
- Transcription regulation
- Ubl conjugation
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi apparatus |
| chromatin |
| nucleus |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| zinc ion binding |
| steroid binding |
| sequence-specific DNA binding |
| nuclear receptor activity |
| nuclear estrogen receptor activity |
| estrogen response element binding |
Sequence
MTMTLHTKASGMALLHQIQANELEPLNRPQLKIPLERPLGEVYMDSSKPAVYNYPEGAAYDFNAAAPASAPVYGQSGLPYGPGSEAAAFGANGLGAFPPLNSVSPSPLVLLHPPPQPLSPFLHPHGQQVPYYLENESSGYAVREAGPPAYYRPNSDNRRQGGRERLASTSDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRNEAVPSGDMRAANLWPSPIMIKHTKKNSPVLSLTADQMISALLEAEPPIIYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLALHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLRSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHFRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPANFGSAPPEDVNQSQLAPTGCTSSHSLQTYYITGEAENFPSTV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 10 | O-linked (GlcNAc) serine |
|
||
| 572 | O-linked (GlcNAc) threonine |
|
||
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ESR-mediated signaling | Bos taurus |
| Estrogen-dependent gene expression | Bos taurus |
| Extra-nuclear estrogen signaling | Bos taurus |
| Mitochondrial unfolded protein response (UPRmt) | Bos taurus |
| Nuclear Receptor transcription pathway | Bos taurus |
| Nuclear signaling by ERBB4 | Bos taurus |
| Ovarian tumor domain proteases | Bos taurus |
| PI3K/AKT Signaling | Bos taurus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Bos taurus |
| RUNX1 regulates estrogen receptor mediated transcription | Bos taurus |
