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Cytosolic purine 5'-nucleotidase

Summary

UniProt ID

P49902

Gene Symbol

NT5C2
NT5B
NT5CP
PNT5

Organism

Homo sapiens (human)

External Links

GlyGen: P49902
PubChem: P49902
The Human Metabolome Database: HMDBP03750
The O-GlcNAc Database: P49902

Annotation

Keyword

3D-structure
ATP-binding
Allosteric enzyme
Alternative splicing
Cytoplasm
Disease variant
Hereditary spastic paraplegia
Hydrolase
Magnesium
Metal-binding
Nucleotide metabolism
Phosphoprotein
Reference proteome
Transferase

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
negative regulation of defense response to virus by host
protein K48-linked ubiquitination
allantoin metabolic process
GMP metabolic process
IMP catabolic process
IMP metabolic process
dGMP metabolic process
adenosine metabolic process

Displaying **all 2** entries
GO Term
cytoplasm
cytosol

Displaying **all 9** entries
GO Term
metal ion binding
nucleoside phosphotransferase activity
IMP 5'-nucleotidase activity
GMP 5'-nucleotidase activity
identical protein binding
ATP binding
5'-nucleotidase activity
ubiquitin protein ligase activity
XMP 5'-nucleosidase activity

Annotation information from UniProt.

Sequence

MSTSWSDRLQNAADMPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDINEMESPLATRNRTSVDFKDTDYKRHQLTRSISEIKPPNLFPLAPQEITHCHDEDDDEEEEEEEE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites