Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
Summary
- UniProt ID
- P50213
- Gene Symbol
-
- IDH3A
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P50213
- PubChem
- P50213
- The Human Metabolome Database
- HMDBP00899
- The O-GlcNAc Database
- P50213
- O-GlcNAcAtlas
- P50213
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Direct protein sequencing
- Disease variant
- Magnesium
- Manganese
- Metal-binding
- Mitochondrion
- NAD
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Retinitis pigmentosa
- Transit peptide
- Tricarboxylic acid cycle
- Gene Ontology (GO)
| GO Term |
|---|
| carbohydrate metabolic process |
| tricarboxylic acid cycle |
| isocitrate metabolic process |
| GO Term |
|---|
| nucleus |
| mitochondrion |
| mitochondrial matrix |
| mitochondrial isocitrate dehydrogenase complex (NAD+) |
| GO Term |
|---|
| NAD binding |
| magnesium ion binding |
| isocitrate dehydrogenase (NAD+) activity |
Sequence
MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 69 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Citric acid cycle (TCA cycle) | Homo sapiens |
| Mitochondrial protein degradation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:936 | brain disease | |
| DOID:0050572 | cone-rod dystrophy | |
| DOID:0050635 | alternating hemiplegia of childhood | |
| DOID:0050782 | Zollinger-Ellison syndrome | |
| DOID:10003 | sensorineural hearing loss | |
| DOID:10124 | corneal disease | |
| DOID:10126 | keratoconus | |
| DOID:10141 | obsolete asthenopia | |
| DOID:10584 | retinitis pigmentosa | |
| DOID:1059 | intellectual disability |
