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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
N-sulphoglucosamine sulphohydrolase
Summary
- UniProt ID
- P51688
- Gene Symbol
-
- SGSH
- HSS
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P51688
- PubChem
- P51688
- The Human Metabolome Database
- HMDBP01587
- The O-GlcNAc Database
- P51688
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydrolase
- Lysosome
- Metal-binding
- Mucopolysaccharidosis
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| glycosaminoglycan catabolic process |
| heparan sulfate proteoglycan catabolic process |
| determination of adult lifespan |
| motor behavior |
| GO Term |
|---|
| lysosomal lumen |
| lysosome |
| extracellular exosome |
| GO Term |
|---|
| glycosaminoglycan binding |
| metal ion binding |
| N-sulfoglucosamine sulfohydrolase activity |
| N-acetylglucosamine-6-sulfatase activity |
Sequence
MSCPVPACCALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNEL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 41 | N-linked (GlcNAc...) asparagine | |||
| 142 | N-linked (GlcNAc...) asparagine | |||
| 151 | N-linked (GlcNAc...) asparagine |
|
||
| 264 | N-linked (GlcNAc...) asparagine | |||
| 407 |
|
|||
| 413 | N-linked (GlcNAc...) asparagine |
G62765YT
G74724QE
G87389XI
G80920RR
G31852PQ
G03238UC
G41247ZX
G02815KT
G92050GC
G28681TP
G49108TO
G92275SC
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| HS-GAG degradation | Homo sapiens |
| MPS IIIA - Sanfilippo syndrome A | Homo sapiens |
Human Protein Atlas