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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tumor necrosis factor
Summary
- UniProt ID
- P51742
- Gene Symbol
-
- TNF
- TNFA
- TNFSF2
- Organism
- Canis lupus familiaris (dog)
External Links
- PubChem
- P51742
Annotation
- Keyword
-
- Cell membrane
- Cytokine
- Disulfide bond
- Glycoprotein
- Myristate
- Phosphoprotein
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cell surface |
| extracellular space |
| plasma membrane |
| GO Term |
|---|
| cytokine activity |
| tumor necrosis factor receptor binding |
Sequence
MSTESMIRDVELAEEPLPKKAGGPPGSRRCFCLSLFSFLLVAGATTLFCLLHFGVIGPQREELPNGLQLISPLAQTVKSSSRTPSDKPVAHVVANPEAEGQLQWLSRRANALLANGVELTDNQLIVPSDGLYLIYSQVLFKGQGCPSTHVLLTHTISRFAVSYQTKVNLLSAIKSPCQRETPEGTEAKPWYEPIYLGGVFQLEKGDRLSAEINLPNYLDFAESGQVYFGIIAL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 80 | O-linked (GalNAc...) serine; in soluble form |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of TNFR1 signaling | Canis familiaris |
| TNF signaling | Canis familiaris |
| TNFR1-induced NF-kappa-B signaling pathway | Canis familiaris |
| TNFR1-induced proapoptotic signaling | Canis familiaris |
| TNFR1-mediated ceramide production | Canis familiaris |
| TNFR2 non-canonical NF-kB pathway | Canis familiaris |
