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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
6-phosphogluconate dehydrogenase, decarboxylating
Summary
- UniProt ID
- P52209
- Gene Symbol
-
- PGD
- PGDH
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Gluconate utilization
- NADP
- Oxidoreductase
- Pentose shunt
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| D-gluconate catabolic process |
| pentose-phosphate shunt |
| pentose-phosphate shunt, oxidative branch |
| pentose biosynthetic process |
| GO Term |
|---|
| nucleus |
| extracellular exosome |
| cytosol |
| GO Term |
|---|
| NADP binding |
| phosphogluconate dehydrogenase (decarboxylating) activity |
Sequence
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 50 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| NFE2L2 regulates pentose phosphate pathway genes | Homo sapiens |
| Pentose phosphate pathway | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110045 | Alzheimer's disease 12 | |
| DOID:0110046 | Alzheimer's disease 13 | |
| DOID:0110047 | Alzheimer's disease 14 | |
| DOID:0110048 | Alzheimer's disease 15 | |
| DOID:0110858 | polycystic kidney disease 1 | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:0111253 | neurofibromatosis 1 | |
| DOID:10241 | thalassemia | |
| DOID:10629 | microphthalmia | |
| DOID:10652 | Alzheimer's disease |
