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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pyruvate kinase PKM
Summary
- UniProt ID
- P52480
- Gene Symbol
-
- Pkm
- Pk3
- Pkm2
- Pykm
- Organism
- Mus musculus (house mouse)
External Links
- GlyGen
- P52480
- PubChem
- P52480
- The Human Metabolome Database
- HMDBP13273
- RaftProt
- P52480
- O-GlcNAcAtlas
- P52480
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Allosteric enzyme
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Glycolysis
- Hydroxylation
- Isopeptide bond
- Kinase
- Magnesium
- Metal-binding
- Methylation
- Nucleus
- Phosphoprotein
- Potassium
- Pyruvate
- Reference proteome
- S-nitrosylation
- Translation regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| rough endoplasmic reticulum |
| cytosol |
| nucleus |
| cytoplasm |
| mitochondrion |
| cilium |
| myelin sheath |
| collagen-containing extracellular matrix |
| pyruvate kinase complex |
| GO Term |
|---|
| transcription coactivator activity |
| histone H3T11 kinase activity |
| magnesium ion binding |
| mRNA binding |
| pyruvate kinase activity |
| ATP binding |
| potassium ion binding |
| identical protein binding |
| protein homodimerization activity |
| ADP binding |
Sequence
MPKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLNAWAEDVDLRVNLAMDVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Glycolysis | Mus musculus |
| Neutrophil degranulation | Mus musculus |
| Pyruvate metabolism | Mus musculus |
| Regulation of pyruvate metabolism | Mus musculus |
