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Neurocan core protein

Summary

UniProt ID

P55066

Gene Symbol

Ncan
Cspg3

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003696

GlyConnect

2545

GlyGen

P55066

RaftProt

P55066

Annotation

Keyword

Calcium
Cell adhesion
Disulfide bond
EGF-like domain
Hyaluronic acid
Immunoglobulin domain
Lectin
Proteoglycan
Reference proteome
Repeat
Secreted
Signal
Sushi

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
glial cell differentiation
modulation of chemical synaptic transmission
regulation of synapse structural plasticity
regulation of postsynapse organization
positive regulation of neuroblast proliferation
skeletal system development
cell adhesion
central nervous system development

Displaying **all 7** entries
GO Term
extracellular space
plasma membrane
synapse
perineuronal net
perisynaptic extracellular matrix
glutamatergic synapse
GABA-ergic synapse

Displaying **all 3** entries
GO Term
calcium ion binding
carbohydrate binding
hyaluronic acid binding

Annotation information from UniProt.

Sequence

MGAGSVWASGLLLLWLLLLVAGDQDTQDTTATEKGLRMLKSGSGPVRAALAELVALPCFFTLQPRLSSLRDIPRIKWTKVQTASGQRQDLPILVAKDNVVRVAKGWQGRVSLPAYPRHRANATLLLGPLRASDSGLYRCQVVKGIEDEQDLVTLEVTGVVFHYRAARDRYALTFAEAQEACRLSSATIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPITQSRPGCYGDRSSLPGVRSYGRRDPQELYDVYCFARELGGEVFYVGPARRLTLAGARAQCQRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRFANRTGFPAPGARFDAYCFRAHHHTAQHGDSEIPSSGDEGEIVSAEGPPGRELKPSLGEQEVIAPDFQEPLMSSGEGEPPDLTWTQAPEETLGSTPGGPTLASWPSSEKWLFTGAPSSMGVSSPSDMGVDMEATTPLGTQVAPTPTMRRGRFKGLNGRHFQQQGPEDQLPEVAEPSAQPPTLGATANHMRPSAATEASESDQSHSPWAILTNEVDEPGAGSLGSRSLPESLMWSPSLISPSVPSTESTPSPKPGAAEAPSVKSAIPHLPRLPSEPPAPSPGPSEALSAVSLQASSADGSPDFPIVAMLRAPKLWLLPRSTLVPNMTPVPLSPASPLPSWVPEEQAVRPVSLGAEDLETPFQTTIAAPVEASHRSPDADSIEIEGTSSMRATKHPISGPWASLDSSNVTMNPVPSDAGILGTESGVLDLPGSPTSGGQATVEKVLATWLPLPGQGLDPGSQSTPMEAHGVAVSMEPTVALEGGATEGPMEATREVVPSTADATWESESRSAISSTHIAVTMARAQGMPTLTSTSSEGHPEPKGQMVAQESLEPLNTLPSHPWSSLVVPMDEVASVSSGEPTGLWDIPSTLIPVSLGLDESVLNVVAESPSVEGFWEEVASGQEDPTDPCENNPCLHGGTCHTNGTVYGCSCDQGYAGENCEIDIDDCLCSPCENGGTCIDEVNGFICLCLPSYGGSLCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFINSFGHENSWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLVGVRKIKYNVHATVRYQCDEGFSQHRVATIRCRNNGKWDRPQIMCIKPRRSHRMRRHHHHPHRHHKPRKEHRKHKRHPAEDWEKDEGDFC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

1

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Position	Description	GlyTouCan ID	Source
74		G18588YS G39581TV G56199WZ G94138GR G90665LO G32169KA G27479MZ G19652EM G48414YA G17720FO G82517EK G30208WJ G02846FR G06356OH G50045TK	GlyConnect
121	N-linked (GlcNAc...) asparagine	G06356OH G23294PN G84820NF G05724UK G33609NS G39188ZX G02815KT G06110VR G66538GV G14669DU G63628AV G32550BI G71838YU	GlycoProtDB UniProt GlyGen GlyConnect
235		G18588YS G39581TV G56199WZ G94138GR G90665LO G32169KA G27479MZ G17720FO G82517EK G30208WJ G02846FR G06356OH G50045TK	GlyConnect
339	N-linked (GlcNAc...) asparagine		UniProt GlyGen
380	O-linked (Xyl...) (chondroitin sulfate) serine		UniProt GlyGen
410	O-linked (Xyl...) (chondroitin sulfate) serine		UniProt GlyGen
480			GlyGen
584			GlyGen
742	N-linked (GlcNAc...) asparagine		UniProt GlyGen
978	N-linked (GlcNAc...) asparagine		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
A tetrasaccharide linker sequence is required for GAG synthesis	Mus musculus
CS/DS degradation	Mus musculus
Chondroitin sulfate biosynthesis	Mus musculus
Dermatan sulfate biosynthesis	Mus musculus
ECM proteoglycans	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements