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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neurocan core protein
Summary
- UniProt ID
- P55067
- Gene Symbol
-
- Ncan
- Cspg3
- Organism
- Rattus norvegicus (Norway rat)
External Links
- GlyGen
- P55067
Annotation
- Keyword
-
- Calcium
- Cell adhesion
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Hyaluronic acid
- Immunoglobulin domain
- Lectin
- Proteoglycan
- Reference proteome
- Repeat
- Secreted
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| synapse |
| glutamatergic synapse |
| GABA-ergic synapse |
| perineuronal net |
| perisynaptic extracellular matrix |
| GO Term |
|---|
| carbohydrate binding |
| calcium ion binding |
| hyaluronic acid binding |
Sequence
MGAESVWASGLLVLWLLLLVSGDQDTQDTTTTEKGLHMLKSGSGPIQAALAELVALPCFFTLQPRQSPLGDIPRIKWTKVQTASGQRQDLPILVAKDNVVRVAKGWQGRVSLPAYPRHRANATLLLGPLRASDSGLYRCQVVKGIEDEQDLVTLEVTGVVFHYRAARDRYALTFAEAQEACHLSSATIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPITQSRPGCYGDRSSLPGVRSYGRRDPQELYDVYCFARELGGEVFYVGPARRLTLAGARALCQRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGSAPGVRTVYRFANRTGFPAPGARFDAYCFRAHHHTPQRGDSEIPSSGDEGEIVSAEGPPAPELKPRLGEQEVITPDFQEPLVSSGEDEPLDLTRTQASQETLASTPGGPTLASWLLTGVTSSTGVPSPSSLGVDMEETTPSGTQVAPTPTMRRGRFKGLNGRHFQQQGPEDQLLEAAEASAQPPTLEVTADHMGPSAATEALESDQSHSPWAILTNEVDVPGAGSLGSRSLPESRKWSPSLISPSTVPSTDSTPGLKPGADEAPGVKSAIHHPPWLPSEPAVPSSIPSEALSAVSLQASPGDGSPDFPIVAMLRAPKLWLLPHSTLVPNVSPIPLSPASPLPSSVPEEQAVRPVSFGAEDPETPFQTTMAAPGEASHGSPEADSIEIEGISSMQATKHPISGPWASLDSSNVTVNPVPSDAGILGTESGVLDLPGSPTSDGQATVDMVLATWLPLPGHGLDTGSQSTPMEAHGVTMSVEPTVALEGGATKDPMEATMDVVPSTVDATSGSEPKSSISSTHVVVTAAGDQGTPTLTPTSSEGQVVAQESLGTLTSLPSHPWSSLASSMDEVASVSSGEPTRLWDIPSTLIPVSLGLDESDLKVVAESPGLEGFWEEVASGQEDPTDPCENNPCLHGGTCRTNGTMYGCSCDQGYAGENCEIDIDDCLCSPCENGGTCIDEVNGFICLCLPSYGGNLCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAERDCRRRAGHLTSVHSPEEHKFINSFGHENSWIGLNDRTVERDFQWTDNTGLQYENWREKQPDNFFAGGEDCVVMVAHENGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLVGVRKVKYNVHATVRYQCDEGFSQHHVATIRCRSNGKWDRPQIVCTKPRRSHRMRRHHHHPHRHHKPRKEHRKHKRHPAEDWEKDEGDFC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 121 | N-linked (GlcNAc...) asparagine | |||
| 339 | N-linked (GlcNAc...) asparagine |
|
||
| 380 | O-linked (Xyl...) (chondroitin sulfate) serine |
|
||
| 410 | O-linked (Xyl...) (chondroitin sulfate) serine |
|
||
| 737 | N-linked (GlcNAc...) asparagine |
|
||
| 944 | O-linked (Xyl...) (chondroitin sulfate) serine |
|
||
| 967 | N-linked (GlcNAc...) asparagine |
|
||
| 1164 | N-linked (GlcNAc...) asparagine |
|
G02815KT
G55220VL
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Rattus norvegicus |
| CS/DS degradation | Rattus norvegicus |
| Chondroitin sulfate biosynthesis | Rattus norvegicus |
| Dermatan sulfate biosynthesis | Rattus norvegicus |
| ECM proteoglycans | Rattus norvegicus |
