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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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MIRAGE
Caspase-9
Summary
- UniProt ID
- P55211
- Gene Symbol
-
- CASP9
- MCH6
- Gene ID
- 842
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Apoptosis
- Phosphoprotein
- Reference proteome
- Thiol protease
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| caspase complex |
| apoptosome |
| nucleus |
| cytoplasm |
| mitochondrion |
| protein-containing complex |
| cytosol |
Sequence
MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 337 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| AKT phosphorylates targets in the cytosol | Homo sapiens |
| Activation of caspases through apoptosome-mediated cleavage | Homo sapiens |
| Constitutive Signaling by AKT1 E17K in Cancer | Homo sapiens |
| Formation of apoptosome | Homo sapiens |
| Ligand-independent caspase activation via DCC | Homo sapiens |
| NOD1/2 Signaling Pathway | Homo sapiens |
| Regulation of the apoptosome activity | Homo sapiens |
| SMAC (DIABLO) binds to IAPs | Homo sapiens |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11054 | urinary bladder cancer | |
| DOID:14330 | Parkinson's disease | |
| DOID:1793 | pancreatic cancer | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:9256 | colorectal cancer | |
| DOID:9352 | type 2 diabetes mellitus |
