GO Term |
---|
apoptosome |
nucleus |
cytoplasm |
mitochondrion |
protein-containing complex |
cytosol |
caspase complex |
Position | Description | PubMed ID | GlyTouCan ID | Source |
---|---|---|---|---|
337 |
|
|
Pathway Name | Organism |
---|---|
AKT phosphorylates targets in the cytosol | Homo sapiens |
Activation of caspases through apoptosome-mediated cleavage | Homo sapiens |
Constitutive Signaling by AKT1 E17K in Cancer | Homo sapiens |
Formation of apoptosome | Homo sapiens |
Ligand-independent caspase activation via DCC | Homo sapiens |
NOD1/2 Signaling Pathway | Homo sapiens |
Regulation of the apoptosome activity | Homo sapiens |
SMAC (DIABLO) binds to IAPs | Homo sapiens |
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | Homo sapiens |
DO ID | Disease Name | Source |
---|---|---|
DOID:11054 | urinary bladder cancer | |
DOID:14330 | Parkinson's disease | |
DOID:1793 | pancreatic cancer | |
DOID:3908 | lung non-small cell carcinoma | |
DOID:9256 | colorectal cancer | |
DOID:9352 | type 2 diabetes mellitus |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: April 7, 2025