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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Beta-secretase 1
Summary
- UniProt ID
- P56819
- Gene Symbol
-
- Bace1
- Bace
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- P56819
Annotation
- Keyword
-
- Acetylation
- Aspartyl protease
- Cell membrane
- Cell projection
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Isopeptide bond
- Lysosome
- Palmitate
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| amyloid-beta formation |
| amyloid precursor protein catabolic process |
| amyloid-beta metabolic process |
| cellular response to copper ion |
| cellular response to manganese ion |
| cellular response to amyloid-beta |
| GO Term |
|---|
| lysosome |
| Golgi apparatus |
| plasma membrane |
| membrane |
| axon |
| cytoplasmic vesicle |
| presynapse |
| dendrite |
| cytoplasmic vesicle membrane |
| neuronal cell body |
| GO Term |
|---|
| peptidase activity |
| enzyme binding |
| endopeptidase activity |
| amyloid-beta binding |
| aspartic-type endopeptidase activity |
Sequence
MAPALRWLLLWVGSGMLPAQGTHLGIRLPLRSGLAGPPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKSVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHIPNIFSLQLCGAGFPLNQTEALASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAVSQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTADMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRHQHDDFADDISLLK
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
