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NPC intracellular cholesterol transporter 1

Summary

UniProt ID

P56941

Gene Symbol

NPC1

Organism

Sus scrofa (pig)

External Links

PubChem: P56941

Annotation

Keyword

Cholesterol metabolism
Disulfide bond
Endosome
Glycoprotein
Lipid transport
Lysosome
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
intestinal cholesterol absorption
protein glycosylation
cholesterol metabolic process
cholesterol homeostasis
cholesterol transport
intracellular cholesterol transport
lysosomal transport
bile acid metabolic process
intracellular lipid transport
negative regulation of TORC1 signaling

Displaying **all 8** entries
GO Term
late endosome membrane
endoplasmic reticulum
extracellular region
nuclear envelope
lysosome
lysosomal membrane
plasma membrane
perinuclear region of cytoplasm

Displaying **all 2** entries
GO Term
lipid transporter activity
cholesterol binding

Annotation information from UniProt.

Sequence

MSARGPAFGLLLLLLCPVQVFSQSCVWYGECGIASGDKRYNCRYSGPPKPLPEDGYDLVQELCPGFFFGNVSLCCDVQQLRTLKDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELEYYVGETFANAMYNACRDVEAPSSNEKALGLLCGREAQACNATNWIEYMFNKDNGQAPFTITPIFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPPPVPWRILGLDAMYVIMWSSYMAFLIVFFGAFFAVWCYRKRYFVSEYTPIDGNIAFSVNSSDKGQAFCCDPLGAAFERGLRRLFAQWGAFCVRHPGCVVFFSLAFIVACSSGLVFIRVTTDPVDLWSAPGSQARREKEYFDTHFGPFFRMEQLIIRATNNQSHIYHPYPAGADVPFGPPLSRDILHQVLDLQTAIENITASYNNETVTLQDICLAPLSPYNKNCTILSVLNYFQNSHSVLDHQVGDFFFVYADYHTHFLYCVRAPASLNDASLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWESEFINFVKNYKNPNLTISFMAERSIEDELNRESNSDLFTILISYAIMFLYISIALGHIKSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYIGVPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGGLSVVPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNRLDVVCCVQGAEDGAGVQASESCLFRFFKNSYAPLLLKDWMRPIVIAVFVGVLSFSIAVLNKVEIGLDQSLSMPDDSYVMDYFQSLSRYLHAGPPVYFVVEEGHNYTSLKGQNMVCGGLGCNNDSLVQQIFTAAQLDNYTRIGFAPSSWIDDYFDWIKPQSSCCRVYNSTDQFCNASVVDPTCIRCRPLTSEGKQRPQGEDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILGNGSGVGATYFMTYHTVLQASADFIDAMQKARLIASNITRTMGLEASSYRVFPYSVFYVFYEQYLTVIDDTIFNLGVSLGAIFLVTVVLMGCELWATVIMCVTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTLSTKGSRVDRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAIVLLGATHGLIFLPVLLSYIGPSINKAKSLATQERYKGTEREQLLNF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 16 in total

1

2

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Position	Description	Source
70	N-linked (GlcNAc...) asparagine	UniProt
122	N-linked (GlcNAc...) asparagine	UniProt
135	N-linked (GlcNAc...) asparagine	UniProt
185	N-linked (GlcNAc...) asparagine	UniProt
222	N-linked (GlcNAc...) asparagine	UniProt
415	N-linked (GlcNAc...) asparagine	UniProt
452	N-linked (GlcNAc...) asparagine	UniProt
459	N-linked (GlcNAc...) asparagine	UniProt
478	N-linked (GlcNAc...) asparagine	UniProt
898	N-linked (GlcNAc...) asparagine	UniProt