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MIRAGE
Orexin/Hypocretin receptor type 1
Summary
- UniProt ID
- P58307
- Gene Symbol
-
- Hcrtr1
- Gene ID
- 230777
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| GO Term |
|---|
| feeding behavior |
| regulation of cytosolic calcium ion concentration |
| positive regulation of ERK1 and ERK2 cascade |
| neuropeptide signaling pathway |
| GO Term |
|---|
| peptide hormone binding |
| orexin receptor activity |
Sequence
MEPSATPGAQPGVPTSSGEPFHLPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFLIALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGQALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAVMVPQAAVMECSSVLPELANRTRLFSVCDEHWADELYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSEQLEAQHQGLCTEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPGSSARHKSLSLQSRCSVSKVSEHVVLTTVTTVLS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 194 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (q) signalling events | Mus musculus |
| Orexin and neuropeptides FF and QRFP bind to their respective receptors | Mus musculus |
