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Receptor-interacting serine/threonine-protein kinase 2

Summary

UniProt ID

P58801

Gene Symbol

Ripk2
Rip2

Organism

Mus musculus (house mouse)

External Links

GlyGen: P58801
PubChem: P58801
The O-GlcNAc Database: P58801

Annotation

Keyword

ATP-binding
Adaptive immunity
Apoptosis
Cell membrane
Cytoplasm
Endoplasmic reticulum
Innate immunity
Isopeptide bond
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 52 in total

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GO Term
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of macrophage cytokine production
positive regulation of CD4-positive, alpha-beta T cell proliferation
protein homooligomerization
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
nucleotide-binding oligomerization domain containing 1 signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway
response to interleukin-1
response to interleukin-12

Displaying **all 7** entries
GO Term
cytoplasm
cytoskeleton
plasma membrane
protein-containing complex
vesicle
cytosol
endoplasmic reticulum

Displaying entries **1 - 10** of 11 in total

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GO Term
protein serine/threonine kinase activity
signaling receptor binding
caspase binding
protein serine kinase activity
CARD domain binding
LIM domain binding
protein homodimerization activity
JUN kinase kinase kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding

Annotation information from UniProt.

Sequence

MNGDAICSALPPIPYHKLADLHYLSRGASGTVSSARHADWRVRVAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQGHRPDTSEENLPFDIPHRGLMISLIQSGWAQNPDERPSFLKCLIELEPVLRTFEDITFLEAVIQLKKAKIQSSSSTIHLCDKKMDLSLNIPANHPPQEESCGSSLLSRNTGSPGPSRSLSAPQDKGFLSGAPQDCSSLKAHHCPGNHSWDGIVSVPPGAAFCDRRASSCSLAVISPFLVEKGSERPPIGIAQQWIQSKREAIVSQMTEACLNQSLDALLSRDLIMKEDYELISTKPTRTSKVRQLLDTSDIQGEEFAKVVVQKLKDNKQLGLQPYPEVPVLSKAPPSNFPQNKSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Downstream TCR signaling	Mus musculus
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	Mus musculus
NOD1/2 Signaling Pathway	Mus musculus
Ovarian tumor domain proteases	Mus musculus
activated TAK1 mediates p38 MAPK activation	Mus musculus
p75NTR recruits signalling complexes	Mus musculus