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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Summary
- UniProt ID
- P60484
- Gene Symbol
-
- PTEN
- MMAC1
- TEP1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P60484
- PubChem
- P60484
- SwissLipids
- The Human Metabolome Database
- HMDBP01570
- The O-GlcNAc Database
- P60484
- O-GlcNAcAtlas
- P60484
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative initiation
- Alternative splicing
- Apoptosis
- Autism spectrum disorder
- Cell projection
- Cytoplasm
- Disease variant
- Isopeptide bond
- Lipid metabolism
- Lipid-binding
- Neurogenesis
- Nucleus
- Phosphoprotein
- Protein phosphatase
- Reference proteome
- Secreted
- Synapse
- Tumor suppressor
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of protein stability |
| negative regulation of G1/S transition of mitotic cell cycle |
| GO Term |
|---|
| extracellular region |
| nucleus |
| cytoplasm |
| plasma membrane |
| neuron projection |
| cell projection |
| apical plasma membrane |
| PML body |
| Schmidt-Lanterman incisure |
| cytosol |
Sequence
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 227 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Transcriptional Regulation by MECP2 | Homo sapiens |
| Ub-specific processing proteases | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4464 | collecting duct carcinoma | |
| DOID:4465 | papillary renal cell carcinoma | |
| DOID:4467 | clear cell renal cell carcinoma | |
| DOID:4468 | clear cell adenocarcinoma | |
| DOID:4471 | chromophobe renal cell carcinoma | |
| DOID:4473 | sarcomatoid renal cell carcinoma | |
| DOID:4480 | achondroplasia | |
| DOID:4505 | childhood angiosarcoma | |
| DOID:452 | pleomorphic adenoma | |
| DOID:4543 | retrograde amnesia |
