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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Summary
- UniProt ID
- P60484
- Gene Symbol
-
- PTEN
- MMAC1
- TEP1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P60484
- PubChem
- P60484
- SwissLipids
- The Human Metabolome Database
- HMDBP01570
- The O-GlcNAc Database
- P60484
- O-GlcNAcAtlas
- P60484
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative initiation
- Alternative splicing
- Apoptosis
- Autism spectrum disorder
- Cell projection
- Cytoplasm
- Disease variant
- Isopeptide bond
- Lipid metabolism
- Lipid-binding
- Neurogenesis
- Nucleus
- Phosphoprotein
- Protein phosphatase
- Reference proteome
- Secreted
- Synapse
- Tumor suppressor
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| Schmidt-Lanterman incisure |
| cytosol |
| nucleoplasm |
| cytoplasmic side of plasma membrane |
| postsynaptic density |
| myelin sheath adaxonal region |
| dendritic spine |
| extracellular region |
| nucleus |
| cytoplasm |
Sequence
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 227 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Transcriptional Regulation by MECP2 | Homo sapiens |
| Ub-specific processing proteases | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4554 | type C thymoma | |
| DOID:4586 | familial meningioma | |
| DOID:4587 | benign meningioma | |
| DOID:4791 | supratentorial primitive neuroectodermal tumor | |
| DOID:4948 | gallbladder carcinoma | |
| DOID:4588 | secretory meningioma | |
| DOID:4591 | lymphoplasmacyte-rich meningioma | |
| DOID:4594 | microcystic meningioma | |
| DOID:4606 | bile duct cancer | |
| DOID:4607 | biliary tract cancer |
