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Insulin gene enhancer protein ISL-1

Summary

UniProt ID

P61371

Gene Symbol

ISL1

Organism

Homo sapiens (human)

External Links

GlyGen: P61371
PubChem: P61371
The O-GlcNAc Database: P61371

Annotation

Keyword

Activator
DNA-binding
Developmental protein
Differentiation
Homeobox
LIM domain
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 55 in total

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GO Term
neural crest cell migration
outflow tract septum morphogenesis
outflow tract morphogenesis
endocardial cushion morphogenesis
cardiac right ventricle morphogenesis
axonogenesis
heart development
cell population proliferation
positive regulation of cell population proliferation
positive regulation of angiogenesis

Displaying **all 3** entries
GO Term
chromatin
nucleus
cytoplasm

Displaying entries **1 - 10** of 11 in total

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GO Term
metal ion binding
RNA polymerase II-specific DNA-binding transcription factor binding
promoter-specific chromatin binding
nuclear receptor binding
nuclear estrogen receptor binding
bHLH transcription factor binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
sequence-specific double-stranded DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Cardiogenesis	Homo sapiens
Regulation of expression of SLITs and ROBOs	Homo sapiens
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	Homo sapiens