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Guidelines
MIRAGE
Transforming protein RhoA
Summary
- UniProt ID
- P61586
- Gene Symbol
-
- ARH12
- ARHA
- RHO12
- RHOA
- Gene ID
- 387
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P61586
- PubChem
- P61586
- The Human Metabolome Database
- HMDBP01959
- RaftProt
- P61586
- Re-Glyco
- P61586
Annotation
- Keyword
-
- 3D-structure
- ADP-ribosylation
- Cell division
- Cell membrane
- Cell projection
- Cytoskeleton
- Direct protein sequencing
- Disease variant
- Ectodermal dysplasia
- GTP-binding
- Glycoprotein
- Host-virus interaction
- Hydrolase
- Isopeptide bond
- Magnesium
- Methylation
- Nucleus
- Phosphoprotein
- Prenylation
- Proto-oncogene
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cell periphery |
| postsynapse |
| endosome |
| endoplasmic reticulum membrane |
| cytosol |
| apical junction complex |
| focal adhesion |
| cytoplasmic side of plasma membrane |
| lamellipodium |
| midbody |
| GO Term |
|---|
| GTP binding |
| membrane scission GTPase motor activity |
| GTPase activity |
| protein kinase binding |
| myosin binding |
| G protein activity |
Sequence
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLVL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 34 | (Microbial infection) O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230; alternate |
|
||
| 37 | (Microbial infection) O-alpha-linked (GlcNAc) threonine; by C.novyi toxin TcdA; alternate |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| RHOC GTPase cycle | Homo sapiens |
| SLIT2:ROBO1 increases RHOA activity | Homo sapiens |
| Sema4D induced cell migration and growth-cone collapse | Homo sapiens |
| Sema4D mediated inhibition of cell attachment and migration | Homo sapiens |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | Homo sapiens |
| VEGFA-VEGFR2 Pathway | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3459 | breast carcinoma |
