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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
WD repeat-containing protein 5
Summary
- UniProt ID
- P61964
- Gene Symbol
-
- WDR5
- BIG3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Chromatin regulator
- Disease variant
- Host-virus interaction
- Isopeptide bond
- Nucleus
- Reference proteome
- Repeat
- Transcription regulation
- Ubl conjugation
- WD repeat
- Gene Ontology (GO)
| GO Term |
|---|
| nucleoplasm |
| nucleus |
| Set1C/COMPASS complex |
| mitotic spindle |
| MLL3/4 complex |
| ATAC complex |
| histone acetyltransferase complex |
| NSL complex |
| histone methyltransferase complex |
| MLL1/2 complex |
| GO Term |
|---|
| histone binding |
| methylated histone binding |
| histone H3K4 methyltransferase activity |
Sequence
MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 18 |
|
|
||
| 21 |
|
|||
| 82 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | Homo sapiens |
| Cardiogenesis | Homo sapiens |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | Homo sapiens |
| Formation of WDR5-containing histone-modifying complexes | Homo sapiens |
| HATs acetylate histones | Homo sapiens |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | Homo sapiens |
| Neddylation | Homo sapiens |
| PKMTs methylate histone lysines | Homo sapiens |
| RMTs methylate histone arginines | Homo sapiens |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | Homo sapiens |
