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MIRAGE
V-type proton ATPase subunit B, brain isoform
Summary
- UniProt ID
- P62814
- Gene Symbol
-
- Atp6b2
- Atp6v1b2
- Vat2
- Gene ID
- 11966
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Cytoplasm
- Cytoplasmic vesicle
- Direct protein sequencing
- Hydrogen ion transport
- Reference proteome
- Synapse
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| plasma membrane |
| microvillus |
| melanosome |
| myelin sheath |
| cytosol |
| apical plasma membrane |
| ruffle |
| clathrin-coated vesicle membrane |
| vacuolar proton-transporting V-type ATPase, V1 domain |
| GO Term |
|---|
| ATP metabolic process |
| synaptic vesicle lumen acidification |
| GO Term |
|---|
| ATP binding |
| proton-transporting ATPase activity, rotational mechanism |
Sequence
MALRAMRGIVNGAAPELPVPTGGPMAGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFEKNFITQGPYENRTVYETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH
Glycosylation Sites
G27058EU
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Amino acids regulate mTORC1 | Mus musculus |
| Insulin receptor recycling | Mus musculus |
| Ion channel transport | Mus musculus |
| ROS and RNS production in phagocytes | Mus musculus |
| Transferrin endocytosis and recycling | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080720 | autosomal dominant congenital deafness with onychodystrophy | |
| DOID:1826 | epilepsy |
